PURE® Hard Surface Disinfectant Included in Chipotle’s Enhanced Restaurant Procedures

SAN DIEGO (Sept. 27, 2016) – PURE Bioscience, Inc. (OTCQB: PURE), creator of the patented silver dihydrogen citrate (SDC) antimicrobial, today announced that Chipotle Mexican Grill, Inc. has adopted PURE® Hard Surface disinfectant as a food safety solution to eliminate and prevent Norovirus and other viruses and bacteria in all +2,100 of its store locations nationwide.

Chipotle recently began promoting “Our Food Safety Advancements” and its eight-step food safety program in the media. The new food safety program was also discussed in a 9/21/16 NY Times article entitled, “Every Day’s a Safety Drill as Chipotle Woos Customers Back.”

Chipotle’s web site details the “Food Safety Advancements” it has implemented to ensure that its fresh ingredients are as safe as possible. While it does not identify specific product names, the following statement from its web site refers to Chipotle’s adoption and use of PURE Hard Surface: “We have adopted the use of a natural disinfectant that virtually eliminates harmful bacteria and viruses from the restaurant environment.” This is part of Chipotle’s ‘state of the art sanitation procedures,’ as described on its website – see “Enhanced Restaurant Procedures – Protocols for Handling Ingredients and Sanitizing Surfaces in Our Restaurants” http://chipotle.com/foodsafety?_ga=1.209486546.1706161395.1474499247.

Chipotle’s commitment to become a leader in food safety, and implement the industry’s premier systems, is being led by Dr. James L. Marsden, Ph.D., Executive Director of Food Safety at Chipotle. Marsden is one of the nation’s foremost authorities on food safety.

A New Paradigm of Protection

Chipotle adopted PURE Hard Surface disinfectant in part because of its unique, non-toxic SDC-based solution providing superior efficacy in eliminating and preventing Norovirus and other pathogens. PURE Hard Surface disinfectant is being used by Chipotle on surfaces that come in contact with food in both the front and back of the restaurant, as well as other areas susceptible to contamination by bacteria and viruses.

Hank R. Lambert, CEO of PURE said, “We are proud that PURE Hard Surface disinfectant is playing an important role in Chipotle’s state of the art sanitation procedures. From the outset, our goal has been to protect people and protect a company’s brand. Our SDC-based antimicrobial solution solves an immediate need for increased food safety by providing a uniquely effective, environmentally responsible solution.

“Dr. Marsden and Chipotle are establishing safe food processes and practices throughout the Chipotle system, addressing both supply chain safety and the safety of the procedures at restaurants. Dr. Marsden is intimately familiar with the superior ability of PURE’s non-toxic SDC solution to eliminate pathogens, including Norovirus, E. coli, Salmonella, and Listeria in restaurants and their supply chains,” concluded Lambert.

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About PURE Bioscience, Inc.

PURE Bioscience, Inc. is focused on developing and commercializing our proprietary antimicrobial products primarily in the food safety arena — providing solutions to the health and environmental challenges of pathogen and hygienic control. Our technology platform is based on patented stabilized ionic silver, and our initial products contain silver dihydrogen citrate, or SDC. SDC is a broad-spectrum, non-toxic antimicrobial agent, which offers 24-hour residual protection and formulates well with other compounds. As a platform technology, SDC is distinguished from existing products in the marketplace because of its superior efficacy, reduced toxicity and it mitigates bacterial resistance. PURE is headquartered in El Cajon, California (San Diego metropolitan area). Additional information on PURE is available at www.purebio.com.

Forward-looking Statements

Any statements contained in this press release that do not describe historical facts may constitute forward- looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Forward- looking statements inherently involve risks and uncertainties that could cause our actual results to differ materially from any forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to, the Company’s failure to implement or otherwise achieve the benefits of its proposed business initiatives and plans; acceptance of the Company’s current and future products and services in the marketplace, including the Company’s ability to convert successful evaluations and tests into customer orders and customers continuing to place product orders as expected and to expand their use of the Company’s products; the ability of the Company to develop effective new products and receive required regulatory approvals for such products, including the required data and regulatory approvals required to use its SDC-based technology as a direct food contact processing aid in raw meat processing and to expand its use in OLR poultry processing; competitive factors; dependence upon third-party vendors, including to manufacture its products; and other risks detailed in the Company’s periodic report filings with the Securities and Exchange Commission (the SEC), including its Form 10-K for the fiscal year ended July 31, 2015, its Form 10-Q for the first quarter ended October 31, 2015 and its Form 10-Q for the second quarter ended January 31, 2016, and its Form 10-Q for the third quarter ended April 30, 2016. You should not place undue reliance on these forward-looking statements, which speak only as of the date of this press release. By making these forward-looking statements, the Company undertakes no obligation to update these statements for revisions or changes after the date of this release.

Contacts:

Hank Lambert, CEO PURE Bioscience, Inc. 619-596-8600 ext.103 hlambert@purebio.com

Terri MacInnis, VP of IR Bibicoff + MacInnis, Inc. 818-379-8500 terri@bibimac.com

Tom Hemingway, Redwood Investment Group 714-978-4425 tomh@redwoodfin.com

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